Standard Article

Gene Clustering in Eukaryotes

  1. Jeffrey G Lawrence1,
  2. Thomas Blumenthal2

Published Online: 15 JUL 2008

DOI: 10.1002/9780470015902.a0006117.pub2



How to Cite

Lawrence, J. G. and Blumenthal, T. 2008. Gene Clustering in Eukaryotes. eLS. .

Author Information

  1. 1

    University of Pittsburgh, Pittsburgh, Pennsylvania, USA

  2. 2

    University of Colorado, Boulder, Colorado, USA

Publication History

  1. Published Online: 15 JUL 2008

This is not the most recent version of the article. View current version (18 OCT 2013)


Genes are not always organized at random within eukaryotic chromosomes. Multiple mechanisms can lead to the proximity of genes whose products have related functions.


  • gene clustering;
  • gene duplication;
  • operons;
  • polycistronic messages;
  • trans-splicing