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DNA Repair: Evolution

  1. Eugene V Koonin

Published Online: 15 SEP 2006

DOI: 10.1002/9780470015902.a0006119



How to Cite

Koonin, E. V. 2006. DNA Repair: Evolution. eLS. .

Author Information

  1. National Center for Biotechnology Information, Bethesda, Maryland, USA

Publication History

  1. Published Online: 15 SEP 2006


Comparative genomics has brought a new perspective to the origin and evolution of DNA repair. Evolution of repair is connected intimately to the evolution of replication systems but shows much greater plasticity as a result of many lineage-specific gene losses and horizontal gene-transfer events.


  • DNA replication;
  • horizontal gene transfer;
  • lineage-specific gene loss;
  • evolutionary plasticity