Evolutionarily Conserved Noncoding DNA
Published Online: 30 APR 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Jegga, A. G. and Aronow, B. J. 2008. Evolutionarily Conserved Noncoding DNA. eLS. .
- Published Online: 30 APR 2008
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The availability of increasingly complete and accurate genomic sequence data from evolutionarily separated species – as well as diverse strains and ethnic variants within species – is providing an unprecedented opportunity to identify potentially functional regions within genomic noncoding deoxyribonucleic acid (DNA). A variety of bioinformatics tools enable genome-wide detection, characterization and visualization of highly conserved sequences and the occurrence of potentially functional elements within both the conserved and evolved elements.
- phylogenetic conservation;
- Noncoding DNA;
- regulatory region;