ATP-binding Cassette (ABC) Transporter Supergene Family: Genetics and Evolution
Published Online: 15 JUL 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Dean, M. 2008. ATP-binding Cassette (ABC) Transporter Supergene Family: Genetics and Evolution. eLS. .
- Published Online: 15 JUL 2008
The adenosine triphosphate (ATP)-binding cassette (ABC) genes encode transporters that are expressed on the cell membrane or organelle membranes and are involved in the export of substances out of the cell or the movement of compounds inside the cell. Many ABC genes are mutated in human diseases or have a role in drug resistance to cancer chemotherapy.
- ATP-binding cassette;
- drug resistance;
- genetic disease;
- cystic fibrosis;