Drug Metabolism: Evolution
Published Online: 15 SEP 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Nebert, D. W. 2006. Drug Metabolism: Evolution. eLS.
- Published Online: 15 SEP 2006
Advances in molecular biology and genetics have given us a much better understanding of the evolution of drug metabolism. Genes encoding drug-metabolizing enzymes, as well as some drug receptors and transporters, have functioned in many signal transduction pathways in bacteria and yeast and, more recently, in countless critical life processes in plants and animals – events that emerged millions of years before the establishment of pharmaceutical companies and drug stores.
- drug metabolism;
- human populations