Standard Article

Phosphoproteomics

  1. Timothy D Veenstra,
  2. Thomas P Conrads

Published Online: 15 SEP 2006

DOI: 10.1002/9780470015902.a0006210

eLS

eLS

How to Cite

Veenstra, T. D. and Conrads, T. P. 2006. Phosphoproteomics. eLS. .

Author Information

  1. National Cancer Institute, Frederick, Maryland, USA

Publication History

  1. Published Online: 15 SEP 2006

Abstract

While proteomics aims to globally identify and measure the abundances of proteins, the challenge of phosphoproteomics is to determine globally the phosphorylation status of proteins present in the cell. Advances in mass spectrometry and developments in phosphopeptide enrichment methodologies is enabling high-throughput global identification and relative quantitation of phosphopeptides.

Keywords:

  • phosphopeptide;
  • phosphoprotein;
  • phosphoproteome;
  • mass spectrometry