Kinetochore: Structure, Function and Evolution
Published Online: 15 SEP 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Kitagawa, K. 2006. Kinetochore: Structure, Function and Evolution. eLS. .
- Published Online: 15 SEP 2006
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Kinetochores are complexes of centromere DNA and proteins. Spindle microtubules bind to chromosomes at the kinetochore, and these complexes are required for accurate chromosome segregation during mitosis. The human kinetochore is a supramolecular complex of DNA and proteins that is involved in various mitotic activities.
- chromosome segregation;
- spindle checkpoint