Natural Killer T Cells
Published Online: 28 SEP 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Bezbradica, J. S., Van Kaer, L. and Joyce, S. 2007. Natural Killer T Cells. eLS. .
- Published Online: 28 SEP 2007
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Natural killer T (NKT) cells are innate lymphocytes whose functions are regulated by self and foreign glycolipid antigens presented by the antigen-presenting, major histocompatibility complex (MHC)-like molecule CD1d. Activation of NKT cells in vivo results in rapid release of copious amounts of effector cytokines and chemokines with which they regulate innate and adaptive immune responses to pathogens, certain types of cancers and self antigens. Hence, CD1d and NKT cells are potential targets in vaccine concoctions and for immunotherapies against autoimmune diseases.
- CD1d molecules;
- NKT cells;