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Identification of Disease Genes by CGH Microarrays

  1. Joris A Veltman,
  2. Terry Vrijenhoek

Published Online: 16 JUL 2007

DOI: 10.1002/9780470015902.a0020229

eLS

eLS

How to Cite

Veltman, J. A. and Vrijenhoek, T. 2007. Identification of Disease Genes by CGH Microarrays. eLS. .

Author Information

  1. Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Publication History

  1. Published Online: 16 JUL 2007

Abstract

Subtle genomic copy number alterations cause a wide variety of human diseases. Microarray-based genome profiling by comparative genomic hybridization detects these alterations, which makes it an attractive disease gene-identification strategy.

Keywords:

  • array CGH;
  • genomics;
  • microarray;
  • human disease