Standard Article

Protein–protein Interactions: Identification

  1. Matthew E Lopper,
  2. James L Keck

Published Online: 16 JUL 2007

DOI: 10.1002/9780470015902.a0020491



How to Cite

Lopper, M. E. and Keck, J. L. 2007. Protein–protein Interactions: Identification. eLS. .

Author Information

  1. University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA

Publication History

  1. Published Online: 16 JUL 2007


Protein–protein interactions are essential features of biological processes that allow cells to grow, divide and respond to their environment. A variety of methodologies now exist to probe protein–protein interactions in vivo and in vitro.


  • protein–protein interactions;
  • oligomerization;
  • affinity tag;
  • co-immunoprecipitation;
  • protein complex