Standard Article

Glycosidases: Functions, Families and Folds

  1. Susan M Hancock,
  2. Stephen G Withers

Published Online: 28 SEP 2007

DOI: 10.1002/9780470015902.a0020548



How to Cite

Hancock, S. M. and Withers, S. G. 2007. Glycosidases: Functions, Families and Folds. eLS. .

Author Information

  1. University of British Columbia, Vancouver, British Columbia, Canada

Publication History

  1. Published Online: 28 SEP 2007

This is not the most recent version of the article. View current version (15 JUL 2014)


The classification of glycosidases into families and clans on the basis of amino acid sequence has provided a foundation for the analysis of the structures and mechanisms of these important enzymes. This confluence of bioinformatic, structural and mechanistic studies has greatly advanced glycosidase engineering and the development of specific inhibitors.


  • glycosidase;
  • carbohydrate;
  • glycoconjugate;
  • enzyme;
  • hydrolysis