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Evolution of the Mammalian X Chromosome

  1. Paul D Waters1,
  2. Terence J Robinson2

Published Online: 14 MAR 2008

DOI: 10.1002/9780470015902.a0020739



How to Cite

Waters, P. D. and Robinson, T. J. 2008. Evolution of the Mammalian X Chromosome. eLS. .

Author Information

  1. 1

    The Australian National University, Canberra, Australia

  2. 2

    University of Stellenbosch, Matieland, South Africa

Publication History

  1. Published Online: 14 MAR 2008

This is not the most recent version of the article. View current version (15 MAR 2013)


The mammalian X chromosome has a fascinating evolutionary history which is intimately linked to that of the Y chromosome, since both evolved in concert from identical chromosomes. Teasing apart the events of this evolution (and their timing) has been helped greatly by identifying similarities and differences between the X and Y, and by comparing the sex chromosomes of different species.


  • X chromosome;
  • Y chromosome;
  • evolution;
  • X chromosome inactivation;
  • comparative genomics