Standard Article

Transposable Element-driven Duplications during Hominoid Genome Evolution

  1. Bud Mishra

Published Online: 30 APR 2008

DOI: 10.1002/9780470015902.a0020756

eLS

eLS

How to Cite

Mishra, B. 2008. Transposable Element-driven Duplications during Hominoid Genome Evolution. eLS. .

Author Information

  1. New York University, New York, USA

Publication History

  1. Published Online: 30 APR 2008

Abstract

Hominoid genomes exhibit a significant number of large segmental duplications; these and other similar duplications in mammalian genomes are hypothesized to be mediated by transposable elements such as Alus or L1s in hominoids and rodents, respectively. The true evolutionary mechanisms that sculpted these duplications are emerging to be much more subtle and complex.

Keywords:

  • segmental duplications (SD);
  • low-copy repeats (LCR);
  • copy number variations (CNV);
  • transposable elements;
  • rearrangement hotspots