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Intron Evolution in Duplicated Human Genes

  1. Kamel Jabbari,
  2. Edda Rayko

Published Online: 21 DEC 2007

DOI: 10.1002/9780470015902.a0020784



How to Cite

Jabbari, K. and Rayko, E. 2007. Intron Evolution in Duplicated Human Genes. eLS. .

Author Information

  1. Ecole Normale Supérieure, Department of Biology, Paris, France

Publication History

  1. Published Online: 21 DEC 2007

This is not the most recent version of the article. View current version (15 JAN 2013)


This article discusses the fate of introns in human duplicated genes at the compositional genome transition that occurred between fish/amphibian and mammals. Indeed, at that transition, the ancestral copies (the genes of the gene-dense ‘ancestral genome core’) underwent a guanine–cytosine (GC) enrichment to become the genes of the ‘genome core’. These copies had possibly acquired different functions and/or regulations.


  • chromatin;
  • transposon;
  • recombination;
  • isochore;
  • natural selection