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Intron Loss and Gain

  1. Tobias Mourier1,
  2. Daniel C Jeffares2

Published Online: 21 DEC 2007

DOI: 10.1002/9780470015902.a0020785



How to Cite

Mourier, T. and Jeffares, D. C. 2007. Intron Loss and Gain. eLS. .

Author Information

  1. 1

    University of Copenhagen, Copenhagen, Denmark

  2. 2

    Wellcome Trust Sanger Institute, Cambridge, UK

Publication History

  1. Published Online: 21 DEC 2007


Introns, the nonprotein coding regions of genes that are interspersed between protein-coding exons are present in all eukaryotes' genomes. The variation in intron abundance in eukaryotic genomes signifies that intron loss and intron gain have occurred at varying degrees during the evolution of eukaryotes. Intron gain or loss events have been rare in human and other mammalian genomes, but intron loss in other eukaryotes is starting to be understood in terms of the biology of genomes.


  • introns;
  • evolution;
  • genome;
  • eukaryotes