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The Contribution of Transposable Elements to Human Proteins

  1. Jean-Nicolas Volff

Published Online: 14 MAR 2008

DOI: 10.1002/9780470015902.a0020793

eLS

eLS

How to Cite

Volff, J.-N. 2008. The Contribution of Transposable Elements to Human Proteins. eLS. .

Author Information

  1. Institut de Génomique Fonctionnelle de Lyon, Lyon, France

Publication History

  1. Published Online: 14 MAR 2008

Abstract

The human genome contains hundreds of genes with protein-coding exons and even complete open reading frames derived from transposable elements. These genes are involved in major biological processes such as immunity, replication, reproduction, cell proliferation and apoptosis. This demonstrates the importance of transposable elements as a genomic pool of coding sequences for the creation and evolution of gene functions.

Keywords:

  • transposable elements;
  • human genome;
  • molecular domestication;
  • exonization;
  • evolution