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HapMap Project

  1. Bryan J Traynor,
  2. Andrew Singleton

Published Online: 14 MAR 2008

DOI: 10.1002/9780470015902.a0020796

eLS

eLS

How to Cite

Traynor, B. J. and Singleton, A. 2008. HapMap Project. eLS. .

Author Information

  1. National Institutes of Health, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA

Publication History

  1. Published Online: 14 MAR 2008

Abstract

The inception of the International Haplotype Map Project (http://www.hapmap.org/) and completion of stages I and II of this project has led to the production and public dissemination of a map of patterns of human genetic diversity in four populations; Japanese from Tokyo, Central Europeans from Utah, Han Chinese and Yorubans from Nigeria. These data present unprecedented opportunities in human genetics; they provide invaluable information on human evolutionary history and for the first time present a roadmap for mapping genetic variability that underlies complex traits. The invention and application of ultra-high throughput genotyping technologies is beginning to realize this latter goal, even in the early days of this effort the HapMap Project is proving worth the time and resources invested thus far.

Keywords:

  • haplotype;
  • single nucleotide polymorphism;
  • genetics;
  • diversity