Evolution of Alpha Satellite DNA
Published Online: 14 MAR 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Ugarković, Đ. 2008. Evolution of Alpha Satellite DNA. eLS. .
- Published Online: 14 MAR 2008
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Alpha satellite deoxyribonucleic acid (DNA) is based on 171-bp tandem repeats located in the centromeric regions of all primate chromosomes. It evolves through a series of amplification events resulting in the spreading of ‘new’ subfamilies which replace the ‘old’ ones and confer centromere function. Alpha satellite transcripts play an important role in kinetochore formation and the establishment of pericentromeric heterochromatin.
- alpha satellite DNA;
- higher order repeats;
- concerted evolution