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Gene Conversion during Primate Evolution

  1. Yoko Satta

Published Online: 14 MAR 2008

DOI: 10.1002/9780470015902.a0020832



How to Cite

Satta, Y. 2008. Gene Conversion during Primate Evolution. eLS. .

Author Information

  1. The Graduate University for Advanced Studies, Hayama, Kanagawa, Japan

Publication History

  1. Published Online: 14 MAR 2008

This is not the most recent version of the article. View current version (13 JUN 2013)


Gene conversion is a nonreciprocal recombination process. This originally represented a distortion of segregation of alleles in gametocytes. In evolutionary studies, however, this often means ‘the transfer of deoxyribonucleic acid (DNA) sequence information from one locus to another’. In evolutionary processes the gene conversion is frequently observed between tandemly duplicated sequences or between homologous sequences on a same chromosome. Significant roles of gene conversion between functional loci are generally in keeping their sequence and functional similarity in the ‘coevolution’ of interacting molecules. In addition, gene conversion often takes place between a functional gene and pseudogene. This mainly causes diseases, especially in humans.


  • intra/interchromosomal gene conversion;
  • diseases;
  • concerted evolution;
  • functional interaction;
  • gene duplication