Indels in the Evolution of the Human and Chimpanzee Genomes
Published Online: 15 JUL 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Wetterbom, A., Cavelier, L. and Bergström, T. F. 2008. Indels in the Evolution of the Human and Chimpanzee Genomes. eLS. .
- Published Online: 15 JUL 2008
Mutations in the deoxyribonucleic acid (DNA) cause genomic divergence between species and provide a starting point for evolutionary change. There are several sources of sequence variation and here we will focus on insertions and deletions (indels). Such events occur frequently in genomic alignments of humans and chimpanzees and the indel divergence is estimated to 3–5%. In this article, we will discuss some causes behind indels and the possible impact of indels on the evolution of primate genomes. In addition, we will provide some examples of indels that may affect protein function as well as alternative splicing.
- primate evolution;
- alternative splicing