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Recombination and Human Genetic Diversity

  1. Chris CA Spencer

Published Online: 15 JUL 2008

DOI: 10.1002/9780470015902.a0020857

eLS

eLS

How to Cite

Spencer, C. C. 2008. Recombination and Human Genetic Diversity. eLS. .

Author Information

  1. University of Oxford, Department of Statistics, Oxford, UK

Publication History

  1. Published Online: 15 JUL 2008

Abstract

With the advent of genome-wide human genetic data, understanding the role of recombination in determining patterns of genetic diversity is more important than ever before. Hotspots of recombination are now known to be a key component in dictating the structure of diversity in human populations, and recent research suggests they may play a more fundamental role in the evolution of the human genome.

Keywords:

  • recombination;
  • hotspots;
  • haplotype structure;
  • natural selection;
  • genetic diversity