MicroRNAs in Development and Disease
Published Online: 15 JUL 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Staton, A. A. and Giraldez, A. J. 2008. MicroRNAs in Development and Disease. eLS. .
- Published Online: 15 JUL 2008
Micro ribonucleic acids (miRNAs) are small RNAs responsible for selective repression and degradation of mRNAs. Regulation by miRNAs during development facilitates the transition from one stage to the next and can control specialized characteristics of mature cells. When this regulation is disrupted, cancer can result through increases in proliferation and defects in differentiation.
- developmental transition