Comparing the Human and Fish Genomes
Published Online: 30 APR 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Nakatani, Y. and Morishita, S. 2008. Comparing the Human and Fish Genomes. eLS. .
- Published Online: 30 APR 2008
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How have the genomes of vertebrates evolved over the last 600 million years? In 1970, based on limited observations, Ohno postulated that whole genome duplication events took place in early vertebrates and were essential to increasing complexity of vertebrates. This issue, however, remains a biological quandary. Recent rapid progress in sequencing the genomes of many vertebrates has revealed fundamental insights into the evolutionary process, and the comparative genomics of the fish and human genomes is indispensable for providing conclusive support to Ohno's hypothesis.
- comparative genomics;
- chromosome evolution;
- vertebrate genomes