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Comparing the Human and Medaka Genomes

  1. Takashi Sasaki1,
  2. Nobuyoshi Shimizu2

Published Online: 15 JUL 2008

DOI: 10.1002/9780470015902.a0021010

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How to Cite

Sasaki, T. and Shimizu, N. 2008. Comparing the Human and Medaka Genomes. eLS.

Author Information

  1. 1

    Keio University School of Medicine, Tokyo, Japan

  2. 2

    Keio Advanced Research Center for Genome Super Power, Tsukuba, Japan

Publication History

  1. Published Online: 15 JUL 2008

Medaka (Oryzias latipes) is a small teleost fish for which well-established resources for genetic and genomic studies are available, hence, medaka has become an excellent laboratory model animal for life sciences. Comparing the human and medaka genomes provided novel information on the sets of genes, repetitive elements, gene regulatory elements and the evolutionary conserved elements at the nucleotide sequence level. The genomic information implied chromosomal evolution in the vertebrate lineage and the use of medaka for medical science.

Keywords: human; medaka; genome; genes; repetitive elements; evolution