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Recognition and Response in Plant PAMP-Triggered Immunity

  1. Dale Godfrey1,
  2. John P Rathjen2

Published Online: 15 OCT 2012

DOI: 10.1002/9780470015902.a0023725

eLS

eLS

How to Cite

Godfrey, D. and Rathjen, J. P. 2012. Recognition and Response in Plant PAMP-Triggered Immunity. eLS. .

Author Information

  1. 1

    The University of Adelaide, Adelaide, South Australia, Australia

  2. 2

    The Australian National University, Canberra, Australian Capital Territory, Australia

Publication History

  1. Published Online: 15 OCT 2012

Abstract

Pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) describes the first events after pathogen invasion, whereby the plant identifies the presence of an invader and mounts a response. A race ensues in which the pathogen deploys its array of virulence molecules that act in opposition to host defence mechanisms and promote establishment of a pathogenic niche. Since the seminal work identifying the first pathogen receptor, FLAGELLIN-SENSING 2 (FLS2), the field has worked to define receptor complexes and downstream signalling pathways. This article describes recent progress in this area. In addition, many pathogen effectors target the PTI machinery. Thus, identifying PTI components as effector targets helps to validate those molecules as components of the defence machinery. As such, early molecular interactions are key to the outcome of infection. Indeed it is thought that nonhost resistance, in which most plants species are resistant to most pathogens, is likely to be a result of the PTI system.

Key Concepts:

  • Plants have multilayered recognition systems which detect invading pathogens.

  • The first line of recognition involves detection of PAMPs via host pattern-recognition receptors (PRRs).

  • PRRs are transmembrane receptor-like kinases or receptor-like proteins that perceive PAMPs at the cell surface.

  • PRRs act as a major point of control for PTI.

  • Biogenesis and localisation of PRRs to the plasma membrane requires the proteins are processed by the secretory pathway and individual PRRs have varying requirements for endoplasmic reticulum-quality control pathways.

  • Following PAMP perception, a series of downstream defence responses results in PTI.

  • Attenuation of PRR signalling is necessary to restrict immune responses.

Keywords:

  • disease resistance;
  • flagellin;
  • FLS2;
  • PAMP-triggered immunity;
  • PAMP;
  • pattern-recognition receptor;
  • PRR;
  • PTI;
  • signalling pathways