Chapter 1. Clinical Pharmacology of Ageing

  1. Stephen Jackson Professor of Geriatric Medicine1,
  2. Paul Jansen2 and
  3. Arduino Mangoni3
  1. Arduino Mangoni3,
  2. Paul Jansen2 and
  3. Stephen Jackson Professor of Geriatric Medicine1

Published Online: 2 APR 2009

DOI: 10.1002/9780470017975.ch1

Prescribing for Elderly Patients

Prescribing for Elderly Patients

How to Cite

Mangoni, A., Jansen, P. and Jackson, S. (2009) Clinical Pharmacology of Ageing, in Prescribing for Elderly Patients (eds S. Jackson, P. Jansen and A. Mangoni), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470017975.ch1

Editor Information

  1. 1

    Department of Clinical Gerontology, King's College Hospital, London, UK

  2. 2

    Department of Geriatric Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands

  3. 3

    Department of Clinical Pharmacology, Flinders University, Flinders Medical Centre, Adelaide, Australia

Author Information

  1. 1

    Department of Clinical Gerontology, King's College Hospital, London, UK

  2. 2

    Department of Geriatric Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands

  3. 3

    Department of Clinical Pharmacology, Flinders University, Flinders Medical Centre, Adelaide, Australia

Publication History

  1. Published Online: 2 APR 2009
  2. Published Print: 27 MAY 2009

ISBN Information

Print ISBN: 9780470024287

Online ISBN: 9780470017975

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Keywords:

  • clinical pharmacology of ageing;
  • prescribing for elderly patients;
  • age-related changes in pharmacokinetics;
  • inhibition of synthesis of activated vitamin k-dependent clotting factors;
  • adverse drug reactions (ADRS) - cause of morbidity and mortality in elderly patients;
  • polypharmacy versus appropriate prescribing;
  • elderly people - largest consumers of over-the-counter (OTC) medicines;
  • clinical audit - to providing a high quality service

Summary

This chapter contains sections titled:

  • Epidemiology

  • Age-related changes in pharmacokinetics

  • Age-related changes in pharmacodynamics

  • Adverse drug reactions and drug interactions

  • Adherence

  • Polypharmacy versus appropriate prescribing

  • Over-the-counter medicines

  • Prescribing audit

  • Medication review

  • Undertreatment

  • References