Chapter 17. Quality-Adjusted Survival

  1. Peter M. Fayers1,2,
  2. David Machin3,4,5

Published Online: 27 APR 2007

DOI: 10.1002/9780470024522.ch17

Book Title

Quality of Life: The Assessment, Analysis and Interpretation of Patient-Reported Outcomes, Second edition

Quality of Life: The Assessment, Analysis and Interpretation of Patient-Reported Outcomes, Second edition

Additional Information

How to Cite

Fayers, P. M. and Machin, D. (2007) Quality-Adjusted Survival, in Quality of Life: The Assessment, Analysis and Interpretation of Patient-Reported Outcomes, Second edition, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470024522.ch17

Author Information

  1. 1

    University of Aberdeen Medical School, Scotland, UK

  2. 2

    Norwegian University of Science and Technology (NTNU), Trondheim, Norway

  3. 3

    Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore

  4. 4

    School of Health and Related Research, University of Sheffield, England

  5. 5

    United Kingdom Children's Cancer Study Group (UKCCSG), University of Leicester, England

Publication History

  1. Published Online: 27 APR 2007
  2. Published Print: 2 MAR 2007

ISBN Information

Print ISBN: 9780470024508

Online ISBN: 9780470024522

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Keywords:

  • quality-adjusted survival;
  • Visual analogue scales (VAS);
  • standard gamble (SG) method and estimating patient utilities;
  • willingness to pay (WTP) and discrete choice experiments (DCE);
  • multi-attribute theory;
  • Quality-adjusted life years (QALYs);
  • quality-adjusted time without symptoms and toxicity (Q-TWiST) approach;
  • Healthy-years equivalent (HYE);
  • utility approaches and QoL with survival

Summary

This chapter contains sections titled:

  • Introduction

  • Preferences and utilities

  • Multi-attribute utility measures

  • Utility-based instruments

  • Quality-adjusted life years

  • Q-TWiST

  • Sensitivity analysis

  • Prognosis and variation with time

  • Healthy-years equivalent

  • Conclusions

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