Chapter 19. Meta-Analysis

  1. Peter M. Fayers1,2,
  2. David Machin3,4,5

Published Online: 27 APR 2007

DOI: 10.1002/9780470024522.ch19

Book Title

Quality of Life: The Assessment, Analysis and Interpretation of Patient-Reported Outcomes, Second edition

Quality of Life: The Assessment, Analysis and Interpretation of Patient-Reported Outcomes, Second edition

Additional Information

How to Cite

Fayers, P. M. and Machin, D. (2007) Meta-Analysis, in Quality of Life: The Assessment, Analysis and Interpretation of Patient-Reported Outcomes, Second edition, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470024522.ch19

Author Information

  1. 1

    University of Aberdeen Medical School, Scotland, UK

  2. 2

    Norwegian University of Science and Technology (NTNU), Trondheim, Norway

  3. 3

    Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore

  4. 4

    School of Health and Related Research, University of Sheffield, England

  5. 5

    United Kingdom Children's Cancer Study Group (UKCCSG), University of Leicester, England

Publication History

  1. Published Online: 27 APR 2007
  2. Published Print: 2 MAR 2007

ISBN Information

Print ISBN: 9780470024508

Online ISBN: 9780470024522

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CHAPTER TOOLS

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Keywords:

  • systematic overviews and meta-analyses;
  • assessing quality and Cochrane Collaboration;
  • Performance bias;
  • compliance and attrition bias;
  • QoL meta-analyses and QoL improvement;
  • inverse variance weighted or weighted mean difference (WMD) method;
  • publication bias and funnel plots;
  • meta-analyses of QoL endpoints

Summary

This chapter contains sections titled:

  • Introduction

  • Defining objectives

  • Defining outcomes

  • Literature searching

  • Assessing quality

  • Summarising results

  • Measures of treatment effect

  • Combining studies

  • Forest plot

  • Heterogeneity

  • Publication bias and funnel plots

  • Conclusions

  • Further reading

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