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Diagnostic Hematology

Clinical Chemistry

  1. J. Hubbard

Published Online: 15 SEP 2006

DOI: 10.1002/9780470027318.a0508

Encyclopedia of Analytical Chemistry

Encyclopedia of Analytical Chemistry

How to Cite

Hubbard, J. 2006. Diagnostic Hematology. Encyclopedia of Analytical Chemistry. .

Author Information

  1. Texas Technical University, Lubbock, USA

Publication History

  1. Published Online: 15 SEP 2006

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Hematology, in its pure form, is the study of the red blood cells (RBCs), white blood cells (WBCs), and platelets during normal and pathological conditions. Quantitative and qualitative evaluation and interpretation of the formed elements of the blood require a whole blood sample to be counted using automated cell counters based on electrical impedance or laser light scatter techniques. A wide range of disease types can be encountered, such as hereditary, nutritional, metabolic, traumatic, infections and inflammatory conditions, and hormonal, immunological and neoplastic disorders. All these disorders can result in changes to the blood cell profile, which can be used to aid in diagnosis. Most important to the diagnosis of hematological diseases is an in-depth understanding of the different causes of anemia and the pathogenesis of the leukemias.