Electrolytes, Blood Gases, and Blood pH
Published Online: 15 SEP 2006
Copyright © 2000 John Wiley & Sons, Ltd. All rights reserved.
Encyclopedia of Analytical Chemistry
How to Cite
Elser, R. C. 2006. Electrolytes, Blood Gases, and Blood pH. Encyclopedia of Analytical Chemistry. .
- Published Online: 15 SEP 2006
The term electrolytes, in the clinical sense, refers to the principal ionic constituents of blood: sodium (Na+), potassium (K+), chloride (Cl−), and bicarbonate (HCO3−). Technology for the measurement of these ions has evolved from colorimetric and spectrophotometric methods to ion selective sensors. With the evolution of the technology has come an important reduction in the quantity of sample required to make the determination of concentrations of the ions in blood.
The assessment of respiratory function and the acid–base balance of the blood is accomplished by the measurement of pH, PCO2, and PO2. These measurements are usually not made singly, but rather as a combination of determinations made at the same time on the same blood sample.
In critically ill persons, these seven analytes are of major diagnostic importance.