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Capillary Electrophoresis Coupled to Inductively Coupled Plasma-Mass Spectrometry for Elemental Speciation Analysis

Environment: Water and Waste

  1. Xiaoru Wang1,
  2. Frank Sen-Chun Lee2

Published Online: 15 SEP 2006

DOI: 10.1002/9780470027318.a0808

Encyclopedia of Analytical Chemistry

Encyclopedia of Analytical Chemistry

How to Cite

Wang, X. and Lee, F. S.-C. 2006. Capillary Electrophoresis Coupled to Inductively Coupled Plasma-Mass Spectrometry for Elemental Speciation Analysis. Encyclopedia of Analytical Chemistry. .

Author Information

  1. 1

    Xiamen University, Xiamen, China

  2. 2

    Hong Kong Baptist University, Hong Kong, China

Publication History

  1. Published Online: 15 SEP 2006

Abstract

Speciation analysis is a term commonly used to describe the analytical processes of identifying and measuring the different chemical forms of trace elements in the sample. Starting from the mid-1980s, analytical techniques for elemental speciation analysis have been advancing at an accelerated pace owing to the rapid advancement in analytical instrumentation. Such advancement is especially evident in the development of hyphenated techniques, which involve the on-line coupling of a species-specific separation device with an elemental-specific detection system. They are now well accepted as the methods of choice for speciation analysis because of their speed, sensitivity, specificity and resolution. Capillary electrophoresis/inductively coupled plasma mass spectrometry (CE/ICPMS) is one of the newest members of this family of hyphenated techniques which has found increasing applications in speciation analysis in recent years. Until today, chromatography has been the dominant separation technique in hyphenated techniques and the subject has been extensively reviewed. However, literature information on capillary electrophoresis (CE)-based hyphenated techniques is much less available. In this chapter, the current status of CE/ICPMS will be reviewed with emphasis being placed on the interface design, analytical performance and applications of the different versions of the technique in speciation analysis.