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Polymerase Chain Reaction in the Forensic Analysis of DNA

Forensic Science

  1. Charles M. Strom MD PhD

Published Online: 15 SEP 2006

DOI: 10.1002/9780470027318.a1120

Encyclopedia of Analytical Chemistry

Encyclopedia of Analytical Chemistry

How to Cite

Strom, C. M. 2006. Polymerase Chain Reaction in the Forensic Analysis of DNA. Encyclopedia of Analytical Chemistry. .

Author Information

  1. Illinois Masonic Medical Center, Chicago, USA

Publication History

  1. Published Online: 15 SEP 2006

Abstract

This article summarizes the theory behind the uses of DNA analysis for identification purposes. Various techniques are summarized and their strengths and weaknesses are contrasted. The theoretical basis of the polymerase chain reaction (PCR) and various types of PCR reactions are introduced. A table is provided with loci that can be used for the forensic analysis of DNA. The availability of kits is summarized. Finally, a discussion of mitochondrial DNA analysis is performed.