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Nuclear Magnetic Resonance and Nucleic Acid Structures

Nucleic Acids Structure and Mapping

  1. Magdalena Eriksson

Published Online: 15 SEP 2006

DOI: 10.1002/9780470027318.a1417

Encyclopedia of Analytical Chemistry

Encyclopedia of Analytical Chemistry

How to Cite

Eriksson, M. 2006. Nuclear Magnetic Resonance and Nucleic Acid Structures. Encyclopedia of Analytical Chemistry. .

Author Information

  1. Chalmers University of Technology, Gothenburg, Sweden

Publication History

  1. Published Online: 15 SEP 2006

Abstract

Nuclear magnetic resonance (NMR) is one of the most important and widely used techniques for studying nucleic acid structure. With modern techniques, including isotope labeling and multidimensional spectroscopy, structures of large molecules – nucleic acids alone or in complexes, for example with proteins or ligands – can be determined. Here is given an overview of experimental NMR methods for nucleic acids studies, complemented by illustrative examples of DNA, RNA and PNA structures.