Update based on original article by Charles C. Hardin and Andrea F. Moon Encyclopedia of Analytical Chemistry, © 2000, John Wiley & Sons Ltd.
Nucleic Acid Structural Energetics
Nucleic Acids Structure and Mapping
Published Online: 15 DEC 2010
Copyright © 2000 John Wiley & Sons, Ltd. All rights reserved.
Encyclopedia of Analytical Chemistry
How to Cite
Vieregg, J. R. 2010. Nucleic Acid Structural Energetics. Encyclopedia of Analytical Chemistry.
- Published Online: 15 DEC 2010
Nucleic acids perform many functions essential for life, and exhibit a correspondingly diverse array of structures. This article provides an overview of nucleic acid structure, as well as the forces that govern its formation. The current state of knowledge of nucleic acid thermodynamics is discussed, as well as techniques for predicting and designing structures of interest. Experimental methods used to determine the structure of nucleic acids and the thermodynamics of their reactions are also surveyed.
- nucleic acids;
- DNA structure;
- RNA structure;
- RNA thermodynamics;
- RNA folding;
- secondary structure;
- tertiary structure