Flow and Sequential Injection Analysis Techniques in Process Analysis
Process Instrumental Methods
Published Online: 15 SEP 2006
Copyright © 2000 John Wiley & Sons, Ltd. All rights reserved.
Encyclopedia of Analytical Chemistry
How to Cite
Aldstadt, J. H., Olson, D. C., Wolcott, D. K., Marshall, G. D. and Stieg, S. W. 2006. Flow and Sequential Injection Analysis Techniques in Process Analysis. Encyclopedia of Analytical Chemistry. .
- Published Online: 15 SEP 2006
The principles of flow injection analysis (FIA) and sequential injection analysis (SIA) are described as applied to industrial process monitoring. A brief history is followed by an overview of the fundamentals of FIA and SIA, with emphasis on injection methods and membrane-assisted sample processing approaches. A discussion of the design of process instruments focuses on simplicity, maintainability, and software development. Hardware issues affecting autosamplers, fittings, pumps, and valves are also discussed. Issues affecting method development, quality control, and method validation are examined using specific examples from the chlor-alkali and phosphate rock industries. The design and operation of on-line sample interfaces is then described in detail. Applications in the major industrial areas are used as examples – chemical, biotechnology, manufacturing, and environmental. Finally, strengths and weaknesses are delineated and prospects for the future are presented.