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Quantitative Analysis, Infrared

Infrared Spectroscopy

  1. Frédéric Cadet1,
  2. Salvador Garrigues2,
  3. Miguel de la Guardia2

Published Online: 15 SEP 2012

DOI: 10.1002/9780470027318.a5610.pub2

Encyclopedia of Analytical Chemistry

Encyclopedia of Analytical Chemistry

How to Cite

Cadet, F., Garrigues, S. and de la Guardia, M. 2012. Quantitative Analysis, Infrared . Encyclopedia of Analytical Chemistry. .

Author Information

  1. 1

    University of la Réunion, France-Dom, France

  2. 2

    University of Valencia, Burjassot, Spain

Publication History

  1. Published Online: 15 SEP 2012


In this article, after reviewing the different mathematical methods used in quantification, we describe and discuss their respective advantages and inconveniences. First, different examples of applications of infrared (IR) spectroscopy, used with or without other analytical chemistry methods, are presented. Some examples of direct quantitative analysis in food analysis are reviewed: lipids (measurement of unsaturation degrees, lipids determination), carbohydrates, proteins (secondary structures, quantitative analysis). We also focus on original examples of the use of IR spectroscopy combined with enzymes. Second, some examples of Fourier transform infrared (FTIR) analysis coupled with other analytical methods are reviewed in the following fields: FTIR quantification in pharmaceuticals, petroleum, paints, and other industrial products and in the fields of health, environment, and trace compounds analysis.

Finally, we discuss the limitations and perspectives of IR spectroscopy for quantitative analysis. It appears that the most significant developments in the field of quantitative analysis will most probably come through progress in chemometrics and flow analysis (FA) (automation).