Ultrashort Laser-Pulse Medical Imaging
Published Online: 15 DEC 2010
Copyright © 2000 John Wiley & Sons, Ltd. All rights reserved.
Encyclopedia of Analytical Chemistry
How to Cite
Ben-David, M., Cohen, R., Harbater, O., Steinberg, I., Tepper, M. and Gannot, I. 2010. Ultrashort Laser-Pulse Medical Imaging. Encyclopedia of Analytical Chemistry. .
- Published Online: 15 DEC 2010
Short-pulse tunable lasers are powerful tools that enable us to measure photon time of flight, lifetime changes, trigger processes, and operation in a nonionizing spectral range. Monochromatic X-ray radiation can also be achieved with the use of a free-electron laser (FEL). In this case, the amount of hazardous radiation is significantly lowered; however, the resolution is much higher. Therefore, FELs can serve as important tool for various imaging methods in vitro or in vivo. This article covers a few optical imaging methods such as optical tomography, optical coherence tomography (OCT), fluorescence lifetime imaging, FEL X-ray tomography for in vivo imaging, and coherent anti-Stokes Raman spectroscopy (CARS) for accurate chemical structures detection in live cells in vitro. All these imaging and spectral methods became possible only because of these lasers.