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Atmospheric-Pressure Solid Analysis Probe (ASAP)

Mass Spectrometry

  1. Charles N. McEwen

Published Online: 15 MAR 2010

DOI: 10.1002/9780470027318.a9045

Encyclopedia of Analytical Chemistry

Encyclopedia of Analytical Chemistry

How to Cite

McEwen, C. N. 2010. Atmospheric-Pressure Solid Analysis Probe (ASAP). Encyclopedia of Analytical Chemistry. .

Author Information

  1. University of the Sciences in Philadelphia, Philadelphia, PA, USA

Publication History

  1. Published Online: 15 MAR 2010


The atmospheric sample analysis probe (ASAP) is a simple but powerful direct method for the rapid analysis of a wide variety of materials. The method uses standard ion sources provided on commercial mass spectrometers without interfering with the intended operation. In addition to a fundamental description of the ASAP method, material characterization examples, including synthetic compounds, drugs, tissue, polymers, and petroleum, are presented.


  • atmospheric pressure ionization;
  • drugs;
  • polymers;
  • pyrolysis;
  • tissue analysis;
  • polymer additives;
  • SPME;
  • ion mobility;
  • mass spectrometry