Standard Article

Analytical Applications of Ionic Liquids

General Articles

  1. William E. Acree Jr.1,
  2. Laura M. Grubbs2

Published Online: 15 JUN 2012

DOI: 10.1002/9780470027318.a9153

Encyclopedia of Analytical Chemistry

Encyclopedia of Analytical Chemistry

How to Cite

Acree, W. E. and Grubbs, L. M. 2012. Analytical Applications of Ionic Liquids. Encyclopedia of Analytical Chemistry. .

Author Information

  1. 1

    University of North Texas, Department of Chemistry, Denton, TX, USA

  2. 2

    Wesleyan University, USA and Department of Chemistry, Middletown, CT, USA

Publication History

  1. Published Online: 15 JUN 2012


Analytical methods involving ionic liquids (ILs) have significantly increased in recent years, in part because of the unique solubilization and physical properties on this class of organic compounds. This article provides an overview of the different applications of ionic liquids in analytical chemistry. The presentation is divided into a section describing the properties of liquids that are of interest to analytical chemists, followed by nine sections pertaining to simple biphasic liquid-liquid extractions, liquid-phase microextraction methods, ionic liquid-based solid-phase microextractions (SPME), thin layer chromatographic (TLC) and high-performance liquid chromatographic (HPLC) methods, electromigration methods, gas-liquid chromatographic (GLC) methods, supported ionic liquid membrane separations, mass spectrometric methods, electrochemical methods, and spectroscopic methods. Representative samples of each application are given, along with specific references to the ionic liquid used and type of sample analyzed.