Standard Article

Green Solvents for Analytical Separation and Analyses

General Articles

  1. Miguel de la Guardia1,
  2. Sergio Armenta2

Published Online: 15 DEC 2010

DOI: 10.1002/9780470027318.a9179

Encyclopedia of Analytical Chemistry

Encyclopedia of Analytical Chemistry

How to Cite

de la Guardia, M. and Armenta, S. 2010. Green Solvents for Analytical Separation and Analyses. Encyclopedia of Analytical Chemistry. .

Author Information

  1. 1

    University of Valencia, Analytical Chemistry Department, Burjassot, Spain

  2. 2

    Universitat Autonoma de Barcelona, Department of Chemistry, Bellatera, Spain

Publication History

  1. Published Online: 15 DEC 2010


The alternatives to the use of organic solvents that have been offered by the scientific literature reviewed. In order to look at the best solvents from both analytical and sustainable view points, the use of water under superheated conditions, supercritical fluids, renewable organics, ionic liquids, and aqueous solutions of amphiphillic compounds, have been evaluated. As a general conclusion, it can be seen that, at present, green alternatives to the traditional organic solvents employed in analytical separations and analysis that are being well explored are the capabilities of the use of alcohols, supercritical fluids, and superheated water; and remain unexplored tremendous possibilities for the use of ionic liquids and surfactant solutions.


  • green solvents;
  • superheated water;
  • supercritical fluids;
  • ethanol;
  • ionic liquids;
  • amphiphillic compounds