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Analytical Platforms in Metabolomics

Environment: Water and Waste

  1. Feliciano Priego-Capote,
  2. María Dolores Luque de Castro,
  3. Beatriz Álvarez-Sánchez

Published Online: 15 MAR 2012

DOI: 10.1002/9780470027318.a9240

Encyclopedia of Analytical Chemistry

Encyclopedia of Analytical Chemistry

How to Cite

Priego-Capote, F., Luque de Castro, M. D. and Álvarez-Sánchez, B. 2012. Analytical Platforms in Metabolomics. Encyclopedia of Analytical Chemistry. .

Author Information

  1. University of Córdoba, Department of Analytical Chemistry, Córdoba, Spain

Publication History

  1. Published Online: 15 MAR 2012

Abstract

The present importance of metabolomics to go inside the unsolved secrets of living organisms, as a single discipline or together with other omics, has opened interest in analytical platforms to obtain proper metabolomic information. The steps involved in developing these platforms (viz sampling, sample storage, sample preparation, individual metabolites separation, if required, and detection) are critically discussed as a function of the type of organism under study, the type of sample, and the families of metabolites to be analyzed. An overview of the fundamentals of key equipment in metabolomics, such as that based on nuclear magnetic resonance (NMR) spectrometry or mass spectrometry (MS), is also given for better understanding of its usefulness in this discipline.