1. Diversities and Similarities in P450 Systems: An Introduction

  1. Astrid Sigel3,
  2. Helmut Sigel3 and
  3. Roland K. O. Sigel4
  1. Mary A. Schuler1 and
  2. Stephen G. Sligar2

Published Online: 11 MAY 2007

DOI: 10.1002/9780470028155.ch1

The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3

The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3

How to Cite

Schuler, M. A. and Sligar, S. G. (2007) Diversities and Similarities in P450 Systems: An Introduction, in The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3 (eds A. Sigel, H. Sigel and R. K. O. Sigel), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470028155.ch1

Editor Information

  1. 3

    Department of Chemistry, Inorganic Chemistry, University of Basel, Spitalstrasse 51, CH-4056 Basel, Switzerland

  2. 4

    Institute of Inorganic Chemistry, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

Author Information

  1. 1

    Departments of Cell and Developmental Biology, Biochemistry and Plant Biology, 190ERML, 1201 W. Gregory Drive, University of Illinois, Urbana, IL 61801, USA

  2. 2

    Departments of Biochemistry, Chemistry and the College of Medicine, 116 Morrill Hall, MC-119, 505 S. Goodwin Avenue, Urbana, IL 61801, USA

Publication History

  1. Published Online: 11 MAY 2007
  2. Published Print: 23 MAR 2007

ISBN Information

Print ISBN: 9780470016725

Online ISBN: 9780470028155

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Keywords:

  • P450 system diversities and similarities;
  • P450 chemistries;
  • oxygen introduction in biochemical processes;
  • cytochrome monooxygenases (P450s);
  • Arabidopsis CYP71B subfamily;
  • heme-oxygen catalytic landscape;
  • P450s in mediating xenobiotic catabolism in vertebrates;
  • P450 diversity and future biotechnological applications

Summary

This chapter contains sections titled:

  • Oxygenases: Mediators of Biochemical Diversity

  • P450 Superfamily: Diversity at the Sequence Level

  • Diversity of P450 Structures: Folds and Conformations for Functions

  • Diversity in P450 Mechanisms

  • Diversity in Regulation Across the Superfamily

  • Diversity in the Evolution of Common Metabolic Functions

  • Summary and Outlook

  • Acknowledgments

  • Abbreviations

  • References