12. Cytochrome P450 and Steroid Hormone Biosynthesis

  1. Astrid Sigel3,
  2. Helmut Sigel3 and
  3. Roland K. O. Sigel4
  1. Rita Bernhardt1 and
  2. Michael R. Waterman2

Published Online: 11 MAY 2007

DOI: 10.1002/9780470028155.ch12

The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3

The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3

How to Cite

Bernhardt, R. and Waterman, M. R. (2007) Cytochrome P450 and Steroid Hormone Biosynthesis, in The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3 (eds A. Sigel, H. Sigel and R. K. O. Sigel), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470028155.ch12

Editor Information

  1. 3

    Department of Chemistry, Inorganic Chemistry, University of Basel, Spitalstrasse 51, CH-4056 Basel, Switzerland

  2. 4

    Institute of Inorganic Chemistry, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

Author Information

  1. 1

    Institut für Biochemie, Universität des Saarlandes, P. O. Box 151150, D-66041 Saarbrücken, Germany

  2. 2

    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA

Publication History

  1. Published Online: 11 MAY 2007
  2. Published Print: 23 MAR 2007

ISBN Information

Print ISBN: 9780470016725

Online ISBN: 9780470028155

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Keywords:

  • gonadial steroid hormone biosynthesis;
  • steroidogenic P450s;
  • microsomal P450 systems;
  • adrenodoxin reductase (AdR);
  • protein–protein interaction and electron transfer;
  • steroid hormone synthesis in adrenal cortex;
  • cytochrome P450 and steroid hormone biosynthesis

Summary

This chapter contains sections titled:

  • Introduction

  • Steroidogenic P450s

  • Steroid Hormone Biosynthesis in the Adrenal Cortex

  • Steroid Hormone Biosynthesis in the Gonads

  • Extraadrenal and Extragonadal Steroidogenesis

  • Outlook for the Future

  • Acknowledgments

  • Abbreviations

  • References