13. Carbon-Carbon Bond Cleavage by P450 Systems

  1. Astrid Sigel2,
  2. Helmut Sigel2 and
  3. Roland K. O. Sigel3
  1. James J. De Voss and
  2. Max J. Cryle

Published Online: 11 MAY 2007

DOI: 10.1002/9780470028155.ch13

The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3

The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3

How to Cite

De Voss, J. J. and Cryle, M. J. (2007) Carbon-Carbon Bond Cleavage by P450 Systems, in The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3 (eds A. Sigel, H. Sigel and R. K. O. Sigel), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470028155.ch13

Editor Information

  1. 2

    Department of Chemistry, Inorganic Chemistry, University of Basel, Spitalstrasse 51, CH-4056 Basel, Switzerland

  2. 3

    Institute of Inorganic Chemistry, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

Author Information

  1. School of Molecular and Microbial Sciences, University of Queensland, Brisbane, QLD 4072, Australia

Publication History

  1. Published Online: 11 MAY 2007
  2. Published Print: 23 MAR 2007

ISBN Information

Print ISBN: 9780470016725

Online ISBN: 9780470028155

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Keywords:

  • oxygenated carbon cleavage;
  • cleavage alpha to oxygenated carbons;
  • C[BOND]C bond cleavage reaction and P450scc (CYP11A1);
  • carbon-carbon bond cleavage by P450 systems;
  • prostaglandin biosynthesis;
  • P450-mediated C-C bond cleavage reactions;
  • multi-functional biosynthetic P450

Summary

This chapter contains sections titled:

  • Introduction

  • Cleavage Between Oxygenated Carbons

  • Cleavage Alpha to Oxygenated Carbons

  • Cleavage Alpha to Carbon Bearing Nitrogen

  • Carbon-Carbon Bond Cleavage Involving Peroxides

  • General Conclusions

  • Acknowledgments

  • Abbreviations

  • References