5. The Electrochemistry of Cytochrome P450

  1. Astrid Sigel2,
  2. Helmut Sigel2 and
  3. Roland K. O. Sigel3
  1. Alan M. Bond,
  2. Barry D. Fleming and
  3. Lisandra L. Martin

Published Online: 11 MAY 2007

DOI: 10.1002/9780470028155.ch5

The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3

The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3

How to Cite

Bond, A. M., Fleming, B. D. and Martin, L. L. (2007) The Electrochemistry of Cytochrome P450, in The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3 (eds A. Sigel, H. Sigel and R. K. O. Sigel), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470028155.ch5

Editor Information

  1. 2

    Department of Chemistry, Inorganic Chemistry, University of Basel, Spitalstrasse 51, CH-4056 Basel, Switzerland

  2. 3

    Institute of Inorganic Chemistry, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

Author Information

  1. School of Chemistry, Monash University, Clayton, Victoria 3800, Australia

Publication History

  1. Published Online: 11 MAY 2007
  2. Published Print: 23 MAR 2007

ISBN Information

Print ISBN: 9780470016725

Online ISBN: 9780470028155



  • cytochrome P450 electrochemistry;
  • redox titration (potentiometric equilibrium);
  • ligand field stabilization energy;
  • P450 enzyme protein engineering (site-directed mutagenesis);
  • voltammetric (dynamic) measurements;
  • voltammetrically determined reversible potentials;
  • P450BM3 wired to basal plane graphite (BPG) electrode


This chapter contains sections titled:

  • Introduction

  • Redox Titration (Potentiometric Equilibrium) Measurements

  • Voltammetric (Dynamic) Measurements

  • Conclusions

  • Acknowledgments

  • Abbreviations

  • References