Chapter 12. Dorsal Air Sac Model

  1. Carolyn A. Staton2,3,
  2. Claire Lewis4 and
  3. Roy Bicknell5
  1. Sei Yonezawa,
  2. Tomohiro Asai and
  3. Naoto Oku

Published Online: 27 SEP 2007

DOI: 10.1002/9780470029350.ch12

Angiogenesis Assays: A Critical Appraisal of Current Techniques

Angiogenesis Assays: A Critical Appraisal of Current Techniques

How to Cite

Yonezawa, S., Asai, T. and Oku, N. (2006) Dorsal Air Sac Model, in Angiogenesis Assays: A Critical Appraisal of Current Techniques (eds C. A. Staton, C. Lewis and R. Bicknell), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470029350.ch12

Editor Information

  1. 2

    Academic Unit of Surgical Oncology, University of Sheffield Medical School, Sheffield, UK

  2. 3

    Academic Unit of Surgical Oncology, K-Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK

  3. 4

    Academic Unit of Pathology, University of Sheffield Medical School, Sheffield, UK

  4. 5

    Division of Immunity and Infection, University of Birmingham, Birmingham, UK

Author Information

  1. Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Yada, Suruga-ku, Shizuoka 422–8526, Japan

Publication History

  1. Published Online: 27 SEP 2007
  2. Published Print: 15 DEC 2006

ISBN Information

Print ISBN: 9780470016008

Online ISBN: 9780470029350

SEARCH

Keywords:

  • dorsal air sac (DAS) model;
  • photodynamic therapy (PDT);
  • angiogenesis in tumour progression;
  • neovessel-targeted drug carriers;
  • tumour-induced angiogenesis;
  • anti-angiogenic drugs or anti-angiogenic therapies;
  • drug delivery system (DDS);
  • anti-angiogenic therapy

Summary

This chapter contains sections titled:

  • Introduction

  • Preparation of the DAS model

  • Evaluation of anti-angiogenic photodynamic therapy using a DAS model

  • Determination of blood volume or blood flow in the angiogenic site using the DAS model

  • Quantitative or semi-quantitative analysis of angiogenesis in the DAS model

  • Isolation and application of neovessel-targeting probe using DAS model

  • Conclusions

  • References