Chapter 17. Biological and Clinical Implications of Recruitment of Stem Cells into Angiogenesis

  1. Carolyn A. Staton2,3,
  2. Claire Lewis4 and
  3. Roy Bicknell5
  1. Gianluigi Castoldi,
  2. Antonio Cuneo and
  3. Gian Matteo Rigolin

Published Online: 27 SEP 2007

DOI: 10.1002/9780470029350.ch17

Angiogenesis Assays: A Critical Appraisal of Current Techniques

Angiogenesis Assays: A Critical Appraisal of Current Techniques

How to Cite

Castoldi, G., Cuneo, A. and Rigolin, G. M. (2006) Biological and Clinical Implications of Recruitment of Stem Cells into Angiogenesis, in Angiogenesis Assays: A Critical Appraisal of Current Techniques (eds C. A. Staton, C. Lewis and R. Bicknell), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470029350.ch17

Editor Information

  1. 2

    Academic Unit of Surgical Oncology, University of Sheffield Medical School, Sheffield, UK

  2. 3

    Academic Unit of Surgical Oncology, K-Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK

  3. 4

    Academic Unit of Pathology, University of Sheffield Medical School, Sheffield, UK

  4. 5

    Division of Immunity and Infection, University of Birmingham, Birmingham, UK

Author Information

  1. Haematology Section, Department of Biomedical Sciences, University of Ferrara, S. Anna Hospital, Corso Giovecca, 203 44100 Ferrara, Italy

Publication History

  1. Published Online: 27 SEP 2007
  2. Published Print: 15 DEC 2006

ISBN Information

Print ISBN: 9780470016008

Online ISBN: 9780470029350

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Keywords:

  • endothelial progenitor cells (EPCs);
  • angiogenesis and neovascularization in ageing;
  • stem cell recruitment into angiogenesis;
  • mobilization, homing and differentiation of EPCS;
  • stem cell factor and granulocyte-colony stimulating factor (G-CSF);
  • EPC mobilization;
  • EPCs as surrogate biological marker

Summary

This chapter contains sections titled:

  • Introduction

  • Phenotypic and functional characterization of EPCS

  • Mobilization, homing and differentiation of EPCS

  • Ageing

  • Therapeutic applications

  • Conclusions

  • References