Human Brain Activation during Viewing of Dynamic Natural Scenes

  1. Derek J. Chadwick,
  2. Mathew Diamond Organizer and
  3. Jamie Goode
  1. Uri Hasson1 and
  2. Rafael Malach1,2

Published Online: 7 OCT 2008

DOI: 10.1002/9780470034989.ch16

Percept, Decision, Action: Bridging the Gaps: Novartis Foundation Symposium 270

Percept, Decision, Action: Bridging the Gaps: Novartis Foundation Symposium 270

How to Cite

Hasson, U. and Malach, R. (2006) Human Brain Activation during Viewing of Dynamic Natural Scenes, in Percept, Decision, Action: Bridging the Gaps: Novartis Foundation Symposium 270 (eds D. J. Chadwick, M. Diamond and J. Goode), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470034989.ch16

Author Information

  1. 1

    Room 955, Meyer Bldg, Center for Neural Science, New York University, 4 Washington Place, New York, NY 10003, USA

  2. 2

    Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel

Publication History

  1. Published Online: 7 OCT 2008
  2. Published Print: 13 JAN 2006

Book Series:

  1. Novartis Foundation Symposia

Book Series Editors:

  1. Novartis Foundation

ISBN Information

Print ISBN: 9780470012338

Online ISBN: 9780470034989

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Keywords:

  • brain activation during viewing;
  • non-selective activation component;
  • brain activation during viewing;
  • reverse correlation and movie stimuli;
  • region of interest (ROI)

Summary

To what extent do brains of different human individuals operate in a similar manner? Here we explored the organization and function of different brain regions under progressively more natural conditions. Applying an unbiased analysis, in which spatiotemporal activity patterns in one brain were used to ‘model’ activity in another brain, we found a striking level of voxel by voxel synchronization between individuals during free viewing of an audio-visual movie. This intersubject correlation was evident not only in primary and secondary visual and auditory areas, but also in association cortices. The results reveal a surprising tendency of individual brains to ‘tick collectively’ during natural vision. Moreover, our results demonstrate that the unitary nature of conscious experience in fact consists of temporally interleaved and highly selective activations in an ensemble of specialized regions, each of which ‘picks-up’ and analyses its own unique subset of stimuli according to its functional specialization. Applying reverse correlation to the movie stimuli provides a powerful methodology for revealing both known and unexpected functional specializations in those cortical areas activated by the movie.