Metallo-Enzymes and Metallo-Proteins, Chemistry of
Published Online: 15 MAY 2008
Copyright © 2007 John Wiley & Sons, Inc. All rights reserved.
Wiley Encyclopedia of Chemical Biology
How to Cite
Williams, R. J. 2008. Metallo-Enzymes and Metallo-Proteins, Chemistry of. Wiley Encyclopedia of Chemical Biology. 1–8.
- Published Online: 15 MAY 2008
Metallo-enzymes and metallo-proteins are a combination of a metal ion or several metal ions in which the metal ion is strongly held in a protein. Hence, before describing their properties and functions, it is necessary to appreciate which metal ions bind strongly to proteins and exchange slowly. The biological significance of metallo-enzymes is that they are essential catalysts, especially for the metabolism of small molecules such as H2, CH4, CO, N2, and O2, as well as for long-range electron transfer. The control of uptake and the synthesis of their proteins rest with feedback in a series of metallo-proteins.