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Familial Aggregation

Environmental Health

  1. Françoise Seillier-moiseiwitsch

Published Online: 15 SEP 2006

DOI: 10.1002/9780470057339.vaf001m

Encyclopedia of Environmetrics

Encyclopedia of Environmetrics

How to Cite

Seillier-moiseiwitsch, F. 2006. Familial Aggregation. Encyclopedia of Environmetrics. 2.

Author Information

  1. University of North Carolina at Chapel Hill, NC, USA

Publication History

  1. Published Online: 15 SEP 2006


By familial aggregation is meant the occurrence of a disorder at a higher frequency in the relatives of affected individuals than in the general population. This aggregation may be due to genetic, cultural or environmental factors. Assessing whether diseases cluster in families, and searching for the explanation when they do so, are the main questions genetic epidemiologists address.